Biology Reference
In-Depth Information
In addition to understanding naturally occurring systems, research into the applied use of
Wolbachia is also greatly needed. The resurgence of vector-borne diseases has led some to express
pessimism at the prospect of control via existing means (Beaty, 2000; Aultman et al., 2001). Reasons
for the intractability of arthropod-borne diseases to conventional control approaches are multifac-
torial and include a decline in the public-health infrastructure, the emergence of pesticide and drug
resistance in arthropod vectors and parasites, and the legislated reduction of available pesticides
due to environmental and public-health concerns. Thus, there is interest in the development of novel
strategies to complement current control measures. Given recent advances that have moved the
prospect of vector-replacement strategies into the realm of Ñnear-term feasibilityÒ (Handler and
James, 2000; Aultman et al., 2001; Handler, 2001; Kokoza et al., 2001; Ito et al., 2002; Lycett and
Kafatos, 2002), additional attention to appropriate and feasible Wolbachia -based population-
replacement strategies is also needed.
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