Biomedical Engineering Reference
In-Depth Information
Figure 6.67  Plot of D c / g as a function of e .
particle moves a little more slowly than the fluid and the relative velocity is larger
on the wall side; a pressure difference acts on the particle to push it towards the
wall, as well as a spin on the particle associated to the vorticity of the flow. The
expression of this lift force was derived by Rubinow and Keller [31] for a spherical,
rigid particle
3
F
=
π ρ ω
R
´
u
(6.117)
lift
f
where r f is the density of the medium (carrier fluid), ω
is the vorticity of the carrier
flow at the location of the particle, and u is its velocity. For a uniform laminar flow
Figure 6.68  View of the DLD of a cell towards a lysis solution resulting in the lyse of the cell and the
separation of the chromosome from other cell contents.
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