Biomedical Engineering Reference
In-Depth Information
Figure 6.35  Modeling of the internal motion in a plug flow with COMSOL. (Courtesy of E. Favre,
COMSOL.)
6.3  Trajectory Calculation
Computation of transport of substance using the concentration equation requires
that the molecules or particles composing this substance have a small size. Because
gravity is not taken into account in the advection-diffusion equation, the particles
are not allowed to sediment and their size/weight is limited by the sedimentation
size/weight (Chapter 5).
When transporting large biological objects such as cells, proteins, or heavy par-
ticles like some magnetic beads (Chapter 9), gravity has an important influence on
the transport. In such a case, the influence of Brownian motion on the particles is
Figure 6.36  Mixing of two constituents in a drop by electrowetting (open EWOD) displacement
from [15].
 
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