Biomedical Engineering Reference
In-Depth Information
Figure 5.21
Concentration contours at two different times calculated with the numerical software
COMSOL [9], showing the same behavior as that of the analytical approach.
diffusion inside the tube can be reduced. Although this problem is relevant to Chap-
ter 6 (biochemical reactions), it is a diffusion barrier problem and we will mention
it here. We found that if the gap between the annular regions initially labeled with
the primers was adequately functionalized, the recapture of the primers during dif-
fusion would limit the axial diffusion. In Figure 5.23, we have compared the axial
diffusion of primers for a simple, or labeled, gap.
5.3.9 Particle Size Limit: Diffusion or Sedimentation
The following question stems out of an inspection of (5.5): does the gravity force—
which is not present in the equation—affect the diffusion of the microparticles? In
Figure 5.22
Comparison of concentration profiles between analytical and numerical model after
the same time interval.
