Selection of Appropriate Animal Models in Ocular Research: Ocular Anatomy and Physiology of Common Animal Models - Ocular Pharmacology and Toxicology - page 24

Fig. 6 When selecting the appropriate animal model, the target tissue and disease state has to be paired with the most appropriate route of therapy. Secondly, the
route of therapy (i.e., a clinically feasible dosing route and frequency) must be matched to an animal model that would allow clinically valid pharmacokinetic,
pharmacodynamic, efficacy, and toxicology studies to be performed