Biomedical Engineering Reference
In-Depth Information
Fig. 21 Corneal dystrophy in a Dutch Belted rabbit (arrow). This was not present
in pretest examination, but appeared during the study
Fig. 22 Normal anangiotic fundus of the guinea pig
For intraocular procedures or intraocular dosing the specific size of
the globe and the size and volume of all intraocular structures and
the aqueous and vitreous must be understood in order to avoid
inadvertent trauma during the procedure [
39
]. For topical oph-
thalmic dosing, the volume capacity of the conjunctival cul-de-sac
and volume of the pre-corneal tear film must be known.
In addition, the examination and restraint techniques, need for
sedation, type of biomicroscope and indirect ophthalmoscope,
diopter power of the indirect lens, and number of animals that
can be examined in the time period that the mydriatic effect will
persist must be understood. The
role of
the
veterinary
