Compositions, Formulation, Pharmacology, Pharmacokinetics, and Toxicity of Topical, Periocular, and Intravitreal Ophthalmic Drugs - Ocular Pharmacology and Toxicology - page 109

List of other commercially available ophthalmic formulations with their trade names, active ingredient, dosage from strength, inactive
ingredients, type of dosage form, and indicated ocular diseases

% dosage
of active
ingredient

Active
ingredient

Dosage
form

Recommended for
disease treatment

Trade name Inactive ingredients Reference

Azasite ® Azithromycin 1.0 Polycarbophil Eye drops/

solution

Bacterial
conjunctivitis

http://www.merck.com/product/
usa/pi_circulars/a/azasite/
azasite_ppi.pdf

Betoptic
S ® and
Betoptic

Betaxolol 0.25 and/or

0.5

Poly(styrene-divinyl
benzene) sulfonic
acid, carbomer-934P

Eye drops/
solution

Glaucoma http://www.medsafe.govt.nz/

profs/datasheet/b/Betoptic&
Betoptic%20Ssoln.pdf

TobraDex ® Tobramycin/

dexamethasone

0.3/0.1 Tyloxapol and

hydroxyethyl
cellulose

Ophthalmic
suspension

Ocular infections
and inflammations

http://ecatalog.alcon.com/pi/
TobraDexSusp_us_en.pdf

TobraDex ®
ST

Tobramycin/
dexamethasone

0.3/0.05 Xanthan gum Gel-forming

eye drops

Blepharitis http://ecatalog.alcon.com/pi/

TobraDexST_us_en.pdf

Timoptic-
XE ®

Timolol maleate 0.25 and/or

0.5

Gellan gum Eye drops/

solution

Glaucoma http://www.merck.com/product/

usa/pi_circulars/t/timoptic/
timoptic_xe_pi.pdf

Durezol TM Difluprednate 0.05 Polysorbate-80

and castor oil

Emulsion
eye drops

Anterior uveitis and
for inflammation
and pain associated
with ocular surgery

http://ecatalog.alcon.com/pi/
Durezol2012_us_en.pdf

Cationorm ®

- - Light mineral oil,

glycerol, tyloxapol,
poloxamer-188

Eye drops Mild dry eye http://www.santen.eu/eu/

products/therapyareas/dryeye/
Pages/Cationorm.aspx

Nevanac ® Nepafenac 0.1 carbomer 975P and

Tyloxapol

Suspension Pain and inflammation

after cataract surgery

http://www.accessdata.fda.gov/
drugsatfda_docs/label/2011/
021862s008lbl.pdf

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