Biomedical Engineering Reference
In-Depth Information
Fig. 1.4
Tissue modeling
sis is conducted. Then the relationship between all the components is studied at a
more global functional organ level, where contacts, actuation forces, and dynamics
are taken into account. The tissue and joint level simulation components exchange
information in cyclic manner: each component will use (partially) as input the output
of the other component. This simulation framework can be used for different case
scenarios, such as the complex walking simulation. Simulation of deformation and
stress distribution calculation with regards to contact forces, velocities, accelerations
and actuation (muscles) should be established. Improvements on the models of car-
tilage could also be proposed to match tissue mechanical behavior more closely to
measure non-linear behavior. Non-linear biphasicmaterial models of cartilage should
be developed to determine appropriate linear-elastic material properties for a spe-
cific range of loading frequencies to adequately match the time-dependent behavior
of cartilaginous tissue. To this end, specific models with the accuracy of the contin-
