Biomedical Engineering Reference
In-Depth Information
Fig. 5.3
Different grades of osteoarthritis disease obtained using (
a
) microscopic
imaging [
15
]
b
) MRI imaging [
16
], (Fig.
5.3
a reprinted from
Osteoarthritis and
cartilage
, vol. 13, no. 11, Kleemann, R. U. et al., Altered cartilage mechanics
and histology in knee osteoarthritis: relation to clinical assessment (ICRS Grade),
pp. 958-963, 2005, Copyright © 2005 OsteoArthritis Research Society International, with
permission from Elsevier.) (Fig.
5.3
b reprinted from
Arthritis & Rheumatism
, vol. 52, no. 11,
Loeuille, D. et al. Macroscopic and microscopic features of synovial membrane inflammation in
the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity,
pp. 3492-3501, Copyright © 2005, American College of Rheumatology, with permission from
Wiley Online Library.)
and indicating different biological structures. The initial computational evaluation
of physical measurements for visualization of small scale molecular data [
25
]as
well as the theoretical concepts and subsequent additional computations needed for
processing the respective data may be even more complicated than they were in
case of the preceding large scale visualization problems. The molecular visualiza-
tion will result in visualizing certain structural aspects of molecules being consistent
with our current scientific physico-chemical model of the respective molecular and
atomic structures. One might still claim that the latter small scale visualization is
