Environmental Engineering Reference
In-Depth Information
3.4 Summary, Conclusion and Future Outlook
We reviewed some recent findings in the field of biosurface organic chemistry,
by focusing on interfacial chemical reactions on self-assembled monolayers
(SAMs). Although most type of organic reactions can be performed on
SAMs, steric hindrance and diffusion barriers can hamper the yield or rate of
reactions at the surface. Very limited reports exist on biocatalytic methodolo-
gies for surface modification reactions on SAMs. However, advantages of mild
reaction conditions and other inherent advantages of biocatalytic techniques
offer promise in this growing field of biosurface organic chemistry. The
enforced positioning of functional groups in SAMs also has great potential
for selective rate enhancement and inhibition, which may provide links to better
understanding of enzymatic reactions.
Acknowledgments The authors would like to acknowledge the Center of Materials Research
and the NIH Center of Biotechnology and Biomedical Science at Norfolk State University for
its financial support.
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