Recent Applications in Capillary Electrochromatography - Chiral Separations by Capillary Electrophoresis - page 463

Acenocoumarol, warfarin, oxazepam,
praziquantel, pindolol, tetramisole

Particle-based
(commercialized)

Cellulose tris(3,5-dimethylphenyl)
carbamate = Chiralcel OD,
amylose tris(3,5-dimethylphenyl)
carbamate = Chiralpak AD,
cellulose tris-(4-methylbenzoate) =
Chiralcel OJ or amylose tris
[( S )-α- methylbenzylcarbamate] =
Chiralpak AS

45 mM ammonium formate pH 3
(acidic, neutral, bifunctional
compounds) or 5 mM phosphate
pH 11.5 (basic, bifunctional,
neutral compounds) mixed with
70% ACN. Voltage low pH: 20 kV,
high pH: 10 kV

DAD [21]

Warfarin, ibuprofen, hexobarbital,
l urbiprofen, suprofen, methylphenobarbital,
fenoprofen, indoprofen, coumachlor,
2-phenylbutyric acid, 2-phenylpropionic acid

Particle-based
(commercialized)

Amylose tris(3,5-dimethylphenyl)
carbamate = Chiralpak AD or
cellulose tris-(4-methylbenzoate) =
Chiralcel OJ

45 mM ammonium formate pH 2.9/
ACN (35/65); 15 kV

DAD [22]

Acebutolol, alprenolol, ambucetamide,
atropine, betaxolol, bisoprolol, bopindolol,
bupranolol, carazolol, carteolol, celiprolol,
chlorpheniramine, dimethindene, esmolol,
ethopropazine, felodipine, l uoxetine,
labetalol, lorazepam, mebeverine,
meptazinol, metoprolol, mianserine, mori ne,
nadolol, nebivolol, nimodipine, oxazepam,
oxprenolol, pindolol, praziquantel,
promethazine, propiomazine, propranolol,
sotalol, temazepam, tertatolol, tetramisole,
toliprolol, trans -stilbene oxide, verapamil

Particle-based (commercial) Cellulose tris(3,5-dimethylphenyl)

carbamate = Chiralcel OD,
amylose tris(3,5-dimethylphenyl)
carbamate = Chiralpak AD,
cellulose tris-(4-methylbenzoate) =
Chiralcel OJ or amylose tris
[( S )-α- methylbenzylcarbamate] =
Chiralpak AS

5 mM phosphate buffer pH 11.5
mixed with 35%-70% ACN;
Applied voltage between 5 and
25 kV

DAD [23]

Levetiracetam Particle-based Amylose tris(3,5-dimethylphenyl)

carbamate = Chiralpak AD

5 mM phosphate pH 11.5/ACN
(30/70); 10 kV

DAD [25]

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