Biomedical Engineering Reference
In-Depth Information
20
15
10
5
0
-5
-10
0.5
1
1.5
2
2.5
3
3.5
4
4.5
(e)
min
10
5
0
-5
-10
-15
0.5
1
1.5
2
2.5
3
3.5
4
4.5
(f )
min
5
-5
-10
-15
-20
-25
-30
0.5
1
1.5
2
2.5
3
3.5
4
4.5
(g)
min
FIGURE 9.10 (continued)
(e) 1-butanol (1.20% v/v); (f) cyclopentanol (1.19% v/v);
(g) cyclohexanol (1.39% v/v). Other conditions: 2% w/v DDCV; 0.5% v/v ethyl acetate; 50 mM
phosphate buffer, pH 7.0; detection wavelength = 215 ± 5 nm; capillary dimensions:
L
tot
= 32 cm,
L
eff
= 23.6 cm, i.d. = 50 μm; hydrodynamic injection = 25 mbar for 2 s; applied voltage = 11.5 kV.
(From Kahle, K.A. and Foley, J.P.,
Electrophoresis
, 27, 4321, 2006. With permission.)
than achiral associations, leading to decreased mass transfer and lower efi ciency.
The importance of cosurfactant identity optimization based on the compounds of
interest was demonstrated in this publication.
9.4.1.2
N
-undecenoyl-
D
-valinate as the Chiral Surfactant
Unique methods for the preparation of polymeric chiral microemulsions from the
chiral surfactant
N
-undecenoyl-d-valinate (d-SUV) were reported by Iqbal et al. [12].
One technique utilized polymerized d-SUV with 1-butanol and
n
-heptane to form
the microemulsions. The impacts of 1-butanol,
n
-heptane, and poly-d-SUV concen-
trations were examined using binaphthyl, barbiturate, and paveroline derivatives
with different trends in resolution, retention, efi ciency, and enantioselectivity found
for the different analytes. For 1,1
′
-binaphthyl-2,2
′
-diyl hydrogen phosphate (BNP) no
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