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10 7 M 1 )
Table 19.2
Apparent binding constants of ligands to the taxoid site (K b
26 C
27 C
30 C
32 C
35 C
37 C
40 C
42 C
Paclitaxel
2.640.17
2.190.05
1.830.09
1.810.21
1.430.17
1.070.11
0.960.14
0.940.23
Cyclostreptin
1.021.4
1.430.9
1.590.7
2.051.7
2.061.1
2.122.1
2.672.4
2.842.4
Zampanolide
13.72.9
15.00.4
14.34.8
18.77.6
21.49.3
25.811.0
41.617.3
42.417.5
Paclitaxel data from Buey et al. (2004) ; Cyclostreptin data from Edler et al. (2005) ; and Zampanolide data from Field et al. (2012) .
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