Biomedical Engineering Reference
In-Depth Information
where J 0 and J 1 are the Bessel functions (of the first kind) of order 0 and 1, respectively. l n is the n th
positive zero value of the Bessel function J 0 ( l n )
¼
0. C n is a function of the dimensionless potential
J
*:
Z 1
xJ 0 ðl n xÞJ ðxÞ
C n ¼
d x:
(2.154)
x ¼ 0
The boundary conditions for (2.151) are:
r Þ
d r
d
J j r ¼ 1 ¼
z ;
0 :
(2.155)
j r ¼ 0 ¼
The solution for the dimensionless potential is:
I 0 R
l D
r
I 0 R
l D
J ðr Þ¼z
;
(2.156)
i n J 0 ( ix ) are the modified Bessel functions of the first kind and zero order. Substituting
(2.156) into (2.154) results in:
where I 0 ( x )
¼
z
I 0 R
l D
J 1 ð
l n Þ=
I 1 ð
R
=
l D Þ
C n ¼
2 :
(2.157)
l n 1
Rl D
l n
þ
The dimensionless velocity distribution in a cylindrical capillary is then:
R
l D
2
4
3
5 :
2 R
l D
2 I 1
I 0
N
l n r Þ
J 1 ðl n Þ
1
l n
J 0 ð
1
u ðr Þ¼
R
l D
(2.158)
R
l D
2
n
¼
1
l n þ
2.6.1.5 Electrokinetic flow in a rectangular microchannel
Due to the characteristics of microtechnology, many micromixers have a rectangular cross section.
Figure 2.33 shows the model of electrokinetic flow in a rectangular microchannel. The Navier-Stokes
equation and the Poisson-Boltzmann equation are formulated in the Cartesian coordinate system as:
m v 2 u
3E el v 2
sinh ze
v 2 u
vy 2
v 2
J
vz 2 þ
J
vy 2
2 zen N
3
J
k B T
v 2 z þ
¼
¼
:
(2.159)
Following dimensionless variables are introduced:
u
u eo ;
ze
J
k B T ;
zez
k B T ;
z
D h ;
y
D h ;
u ¼
J ¼
z ¼
z ¼
y ¼
(2.160)
where D h ¼
4 WH /( W
þ
H ) is the hydraulic diameter of the microchannel. For simplicity,
the
approximation of sinh ( x )
x is used. As mentioned above, this assumption is correct if the hydraulic
diameter D h is much larger than the Debye length l D or the ion concentration is dilute. At the
molecular scale, this assumption means that the electric energy of the ions is much smaller than their
¼
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