Biomedical Engineering Reference
In-Depth Information
FIGURE 2.12
Dispersion factor f for typical channel geometries versus aspect ratio d/W (after [23] ).
Dutta et al. [23] introduce a factor f into (2.77) to consider the three-dimensional effect of Taylor
dispersion:
d 2 u 2
210 D f
D ¼
D
þ
;
(2.78)
where d
1 for the case of the parallel plate model. The factor f is a function of the aspect
ratio d / W , where d is the characteristic length of the shallow channel height and W is the channel width.
Based on this definition, the longer cross-sectional dimension is considered as channel width; thus,
d / W
¼
2 h and f
¼
1. Using the Aris approach [12] and numerical simulation, the factor f can be determined for
different geometries. Figure 2.12 shows the dispersion factors of typical channel geometries as
a function of the aspect ratio d / W .
Because of the velocity gradient at the sharp corners of a rectangular channel, factor f increases
from f
¼
1.76 in the case of a square channel cross section ( d / W
¼
1) to f
¼
7.95 in the case of a shallow
channel ( W
[
d ). The factor of an elliptical channel cross section can be calculated explicitly as:
W
d
2 24
24 3 2
5 3 4
210
192
þ
;
f
¼
(2.79)
24
12 3 2
p
1
d 2
W 2
where 3
¼
=
is the eccentricity of the geometry.
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