Biomedical Engineering Reference
In-Depth Information
Rhodamine B was used as the dye for visualization of the mixing effect. With an applied voltage of 0 to
900 V and a distance between the two electrodes of 450
m
m, a field strength ranging from 0 to
10 6 V/cm was used. The mixing channel was fabricated in PDMS. The channel depth and width
are 36.5
2
10 6 V/
cm, which is one order of magnitude higher than that required for the configurations depicted in Figs.
7.15 (a) and (b).
m
m and 78
m
m, respectively. EHD instabilities occurred at a field strength of about 1
7.4 DIELECTROPHORETIC DISTURBANCE
The background of DC dielectrophoresis was discussed in Section 2.6.3. Since a DC electric field can
only trap dielectric particles and does not induce instability, mixing application require the stirring
motion of particles induced by AC dielectrophoretic forces. Considering an AC electric field E el ( t )
¼
E el exp(- iut ) with the driving frequency u and a spherical dielectric particle with a radius of r p , the
dielectric force acting on the particle is:
m
1
2 <
E el
f DEP ð
t
Þ¼
ð
u
Þ $ V
(7.36)
represents the real component of a complex number and E el is the complex conjugate of E el .
Due to the frequency dependence of permittivities of both the fluid and the particle, the dipole moment
is also frequency dependent:
where
<
3 p ð
u
Þ
3 f ð
u
Þ
4 p3 f r p
m
¼
E el
(7.37)
3 p ð
u
Þ
2 3 f ð
u
Þ
where 3 f and 3 p are the complex permittivities of the fluid and the particle. The complex permittivity is
defined as:
i s el
u
3
ð
u
Þ¼
3
(7.38)
where s el is the conductivity of the dielectric medium. The term with the complex permittivities is
called the Clausius-Mossotti factor:
3 p ðuÞ3 f ðuÞ
3 p ð
K
ð
u
Þ¼
Þ :
(7.39)
u
Þ
2 3 f ð
u
Integrating (6.36) over time results in the time-averaged DEP force:
3 p ð
u
Þ
3 f ð
u
Þ
2 p3 f r p
E rms
f DEP ¼
Þ V
(7.40)
3 p ð
u
Þþ
2 3 f ð
u
p is the root-mean-square electric field. The Clausius-Mossotti factor can take
any value between -0.5 and 1. That means, the DEP force can change its direction at a critical driving
frequency u c . This critical frequency can be determined by setting the DEP force or the real part of
K ( u ) to zero:
where E rms ¼
E el =
s
ð
s el ; f
s el ;p Þð
s el ; p þ
2 s el ; f Þ
u c ¼
:
(7.41)
ð
3 p
3 f Þð
3 p þ
2 3 f Þ
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