Biomedical Engineering Reference
In-Depth Information
Rhodamine B was used as the dye for visualization of the mixing effect. With an applied voltage of 0 to
900 V and a distance between the two electrodes of 450
m
m, a field strength ranging from 0 to
10
6
V/cm was used. The mixing channel was fabricated in PDMS. The channel depth and width
are 36.5
2
10
6
V/
cm, which is one order of magnitude higher than that required for the configurations depicted in
Figs.
7.15
(a) and (b).
m
m and 78
m
m, respectively. EHD instabilities occurred at a field strength of about 1
7.4
DIELECTROPHORETIC DISTURBANCE
The background of DC dielectrophoresis was discussed in Section 2.6.3. Since a DC electric field can
only trap dielectric particles and does not induce instability, mixing application require the stirring
motion of particles induced by AC dielectrophoretic forces. Considering an AC electric field
E
el
(
t
)
¼
E
el
exp(-
iut
) with the driving frequency
u
and a spherical dielectric particle with a radius of
r
p
, the
dielectric force acting on the particle is:
m
1
2
<
E
el
f
DEP
ð
t
Þ¼
ð
u
Þ
$
V
(7.36)
represents the real component of a complex number and
E
el
is the complex conjugate of
E
el
.
Due to the frequency dependence of permittivities of both the fluid and the particle, the dipole moment
is also frequency dependent:
where
<
3
p
ð
u
Þ
3
f
ð
u
Þ
4
p3
f
r
p
m
¼
E
el
(7.37)
3
p
ð
u
Þ
2
3
f
ð
u
Þ
where
3
f
and
3
p
are the complex permittivities of the fluid and the particle. The complex permittivity is
defined as:
i
s
el
u
3
ð
u
Þ¼
3
(7.38)
where
s
el
is the conductivity of the dielectric medium. The term with the complex permittivities is
called the Clausius-Mossotti factor:
3
p
ðuÞ3
f
ðuÞ
3
p
ð
K
ð
u
Þ¼
Þ
:
(7.39)
u
Þ
2
3
f
ð
u
Integrating (6.36) over time results in the time-averaged DEP force:
3
p
ð
u
Þ
3
f
ð
u
Þ
2
p3
f
r
p
E
rms
f
DEP
¼
Þ
V
(7.40)
3
p
ð
u
Þþ
2
3
f
ð
u
p
is the root-mean-square electric field. The Clausius-Mossotti factor can take
any value between -0.5 and 1. That means, the DEP force can change its direction at a critical driving
frequency
u
c
. This critical frequency can be determined by setting the DEP force or the real part of
K
(
u
) to zero:
where E
rms
¼
E
el
=
s
ð
s
el
;
f
s
el
;p
Þð
s
el
;
p
þ
2
s
el
;
f
Þ
u
c
¼
:
(7.41)
ð
3
p
3
f
Þð
3
p
þ
2
3
f
Þ
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