Biomedical Engineering Reference
In-Depth Information
FIGURE 7.8
Poincar´ section of mixing with two source-sink pairs bounded by a rectangular mixing chamber at different
dimensionless switching time t switch .
(Reprinted with permission from [9] .)
a connecting microchannel. Integrated microheaters evaporates liquid water creating a vapor bubble,
which acts as the actuator. If the heat is removed, the bubble collapses due to condensation. A long
microchannel connects the actuation chamber with the pump chamber, which is located between the two
check valves. This long microchannel prevents the pumped liquid to be affected by the evaporation and
condensation processes in the actuation chamber. The microchannel network depicted in Fig. 7.9 was
fabricated on a planar silicon substrate using deep reactive ion etching (DRIE) and silicon on isolator
(SOI) technology (see Chapter 4). The microheaters are made of polysilicon deposited on a quartz
substrate. The check valves are freely floating silicon structures. The silicon and quartz part are bonded by
adhesive bonding with an epoxy. Subsequent treatment with oxygen plasma free the epoxy blockage in
the microchannels.
Figure 7.10 shows another design of an active micromixer based on pressure-driven disturbance. In
contrast to the monolithic approach of Deshmukh et al., Fujii et al. [11] presented a hybrid approach,
where silicon micropumps are combined with a microchannel network in PDMS. Both the silicon part
and the PDMS part are bonded to a glass plate. Connecting holes are drilled in the glass plate that allow
liquids to be delivered from the pump to the mixing channel. The micromixer has the typical Y-design
with two inlets and a long mixing channel are molded in PDMS using soft lithography technique (see
Section 4.2.2.3). The silicon micropump is a valveless diaphragm pump driven by a piezoelectric
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