Biomedical Engineering Reference
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the shift of half of a channel width. The process repeats with the subsequent groups. The two layers of
the micromixers were fabricated using soft lithography with masters made of silicon and SU-8. The
two PDMS layers are subsequently aligned and bonded with the help of oxygen plasma treatment.
Experimental results showed that best mixing was achieved with a Reynolds number of 10.
Dean vortices in curved channels can rotate mixing streams. This feature can be used to realize
sequential lamination. Figure 6.12 (a) shows the rotating characteristics of a curved channel at high
Dean numbers (De
10). A 180 turn can be achieved with a curved channel of length L and a radius
>
FIGURE 6.12
Micromixers utilizing Dean flow for splitting: (a) a single curved channel for rotation; (b) rotation and split; and
(c) Dean vortex combined with recirculation at a sudden expansion (after [19] ).
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