Biomedical Engineering Reference
In-Depth Information
FIGURE 5.8
Concept of sequential lamination.
where the dimensionless space variable x * and time t * are defined as
x
x *
¼
(5.11)
w
ð
t
Þ
and
Z t
D
wðt 0 Þ
2 d t 0 :
t *
¼
(5.12)
0
t * 1/2 . Thus, the relation for the
The penetration distance d in the ( x *, t *) space is given by dx *
w
penetration distance d x in the ( x , t ) space is
D
W 2 2 a ð
1
2
d x
W exp
Þ ¼
exp 2 at
1
Þ
:
(5.13)
ð
at
Mixing is complete if d x ¼
W final when the diffusive penetration distance is on the same order of the
striation thickness:
D
W 2 2 a ð
1
2
1
¼
exp 2 at
1
Þ
:
(5.14)
The value of a is inversely proportional to the shear rate afu=W ; thus, Pe W f aW 2 / D . At the fully
mixed state [exp(2 at final )
[
1], the required channel length of the mixer would be
L mixer
W f
ln Pe W :
(5.15)
The transformations described above can be achieved either by sequential lamination or by chaotic
advection. Sequential lamination can be implemented by forced splitting and lamination or by chaotic
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