Biomedical Engineering Reference
In-Depth Information
Fig. 1.20
The mean Raman spectra of normal bronchial tissue (n D 12) and malignant adeno-
carcinoma (n D 6) and squamous cell carcinoma (
SCC
, n D 10) bronchial tissue samples. Each
spectrum was normalized to the area under the curve to correct the variations in absolute spectral
intensity (Adapted from Huang et al. [
38
], with permission)
Fig. 1.21
In vivo
NIR Raman spectra of human lung tissue with different pathologies taken with
the HF grating (2-s integration).
a
(
main graph
): smoothed raw spectra.
a
(
inset
): unprocessed raw
data.
b
extracted Raman spectra (spectral response calibrated and normalized). The data above
3;100 cm
1
have been scaled by 0.25. The spectra were shifted along y axis for clarity. Top to
bottom order:
SCC
,
CIS
, moderate dysplasia, and normal tissue for both
a
and
b
(Adapted from
Shortetal.[
39
], with permission)
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