Biomedical Engineering Reference
In-Depth Information
scientific innovation and research in years to come. Therefore, it is essential that
OCT technologies are developed further as an enabling measurement technology.
The functional extension capability of OCT technique such as spectroscopic and
Doppler OCT can provide additional image contrast mechanisms to differentiate
structure and assess functional activity. OCT has the far-reaching potential to be a
quantitative imaging technique that could impact many, as yet unexplored, areas and
should therefore be considered a vital measurement tool. Important emerging fields
already impacted by OCT are those of tissue engineering and polymer composite
manufacture. To realize true optical biopsy and full optical diagnosis and grading
of malignant tumors by OCT will require a great number of clinical trials and
solid experimental demonstration of the robustness of the technique. To enable such
developments, the measurement technique must also be quantitatively validated. In
particular, the clinical potential and reliability of OCT will be greatly enhanced by
validated measurements of volume, structural dimensions, and flow. These stringent
requirements present new and exciting challenges for optical medical metrology.
Clearly, it will not be possible to fulfill all of these criteria immediately. However,
as these issues are addressed, the applicability of OCT can only grow.
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