Biomolecular Computing - Bionanoelectronics: Bioinquiring and Bioinspired Devices - page 205

population of cells has been recently implemented; it is another example of
complex cellular behavior besides that encountered in genetic circuits able to shape
intracellular noise, generate designed patterns, counting cellular events, and so on
[see Danino et al. ( 2010 )] and the references therein). The collective synchronization
is based on placing genes involved in quorum sensing machines and extracted
from Bacillus Thurigensis and Vibrio fischeri , under the control of gene promoters.
These genes generate synchronized oscillations in the population of Escherichia
coli placed in a microfluidic device. These oscillations are robust, persistent, and
fast, with periods as short as 13 min. The oscillation period depends on temperature,
media source, and concentration of inducers in the solution [for details, see Stricker
et al. ( 2008 )]. It was observed that almost every E. coli cell oscillates and that the
oscillatory phase is inherited by daughter cells.
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