Biomedical Engineering Reference
In-Depth Information
Figure 4.4
Illustrations of typical geometrical features probed by NMR. (A) distance
restraints as obtained by NOE measurements, (B) angle restraints as
obtained by RDC or PCS measurements, (C) long-range distance
restraints to a single paramagnetic centre as obtained by PRE or PCS
measurements and (D) local geometry: torsion angles (blue) influence via
the electronic structure the chemical shifts and J-coupling constants. Ring
current (dashed lines) induced magnetic fields modulate chemical shifts to
yield short-range distance and orientation restraints.
