Biomedical Engineering Reference
In-Depth Information
O
NH
2
N
O
O
O
O
O
P
P
F
O
Dylos (
16.7
)
F
N
Tacrine (
16.9
)
O
Sarin (
16.8
)
Donepezil (
16.10
)
N
N
O
O
N
N
H
O
O
H
N
N
Physostigmine (
16.11
)
Eptastigmine (
16.12
)
N
O
N
N
O
O
O
N
H
O
O
N
N
H
HO
Rivastigmine (
16.13
)
Phenserine (
16.14
)
Galanthamine (
16.15
)
H
NH
2
NH
2
NH
O
N
Cl
N
H
O
O
H
Huperzine A (
16.16
)
Huprine X (
16.17
)
Ladostigil (
16.18)
Cl
Cl
O
NH
O
N
H
N
H
O
O
NH
O
2
N
BGC 20-1259 (
16.19
)
(
16.20
)
N
O
N
O
N
N
+
N
+
Decamethonium (
16.22
)
Phenylethylcymserine (
16.21
)
N
+
N
+
NH
2
HO
N
N
OH
N
OH
N
+
N
+
H
2
N
N
+
Cl
-
O
2Cl
-
Propidium (
16.23
)
Pralidoxime (
16.24
)
Obidoxime (
16.25
)
FIGURE 16.5
Chemical structures of selected cholinesterase inhibitors (
16.7-16.23
) and the AChE reactivators
16.24
and
16.25
.
