Biomedical Engineering Reference
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Figure 3.8. Nucleotide sequence alignment comparing the expressed ectodomain of native
P. falciparum
3D7 AMA1 (nPfAMA1, accession number: U65407) to the synthetic yeast codon
optimized (syPfAMA1) and mammalian codon optimized (smPfAMA1) genes. The nucleotide
sequences shown here include the relevant codon changes to correspond to the amino acid
substitutions identified in Fig. 3.7 (lower panel). The accession number for the syPfAMA1 3D7
amino acid sequence is AF512508.
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