Biomedical Engineering Reference
In-Depth Information
120
Seed
fermenter
Vial thaw
/shake flask
Production fermenter
(growth phase)
Production fermenter
(induction phase)
100
80
60
40
20
0
Figure
5.3.
Pareto chart of RPN scores calculated based on a risk-assessment for operational parameters fromdifferent phases during the production
process in the case study. Note: An RPN score
>
20, as indicated by the dotted line, was considered a risk high enough tomerit further characterization.
