Biomedical Engineering Reference
In-Depth Information
QLV and Adaptive QLV models were both suitable when compared against these
data. An additional single, large amplitude ramp-and-hold test performed at a
different loading rate showed that, for this particular tissue, both models provided
suitable predictions. However, minor differences in the two model predictions
were also evident, and careful study would be needed to determine model suit-
ability for loading rates outside of those tested.
In summary, the Adaptive QLV model provides a simple-to-fit nonlinear
alternative to the Fung and Generalized Fung QLV models. Because each of these
three models rests upon a set of assumptions, application of any of these models to
a particular tissue requires careful testing over the range of strains and strain rates
that are of interest for a particular application.
Acknowledgments This work was supported in part by the National Institutes of Health
(HL079165) and by the Johanna D. Bemis trust.
References
1. Taber, L.A.: Biomechanics of growth, remodeling, and morphogenesis. Appl. Mech. Rev. 48,
487 (1995)
2. Taber, L.A.: Biomechanics of cardiovascular development. Ann. Rev. Biomed. Eng. 3(1),
1-25 (2001)
3. Varner, V.D., Taber, L.A.: Not just inductive: a crucial mechanical role for the endoderm
during heart tube assembly. Development 139(9), 1680-1690 (2012)
4. Varner, V.D., Voronov, D.A., Taber, L.A.: Mechanics of head fold formation: investigating
tissue-level forces during early development. Development 137(22), 3801-3811 (2010)
5. Zamir, E.A., Czirok, A., Cui, C., Little, C.D., Rongish, B.J.: Mesodermal cell displacements
during avian gastrulation are due to both individual cell-autonomous and convective tissue
movements. Proc. Natl. Acad. Sci. USA 103(52), 19806-19811 (2006)
6. Thomopoulos, S., Genin, G.M., Galatz, L.M.: The development and morphogenesis of the
tendon-to-bone insertion - what development can teach us about healing. J. Musculoskelet.
Neuronal. Interact. 10(1), 35-45 (2010)
7. Bayly, P.V., Cohen, T.S., Leister, E.P., Ajo, D., Leuthardt, E.C., Genin, G.M.: Deformation
of the human brain induced by mild acceleration. J. Neurotrauma. 22(8), 845-856 (2005)
8. Cohen, T.S., Smith, A.W., Massouros, P.G., Bayly, P.V., Shen, A.Q., Genin, G.M.: Inelastic
behavior in repeated shearing of bovine white matter. J. Biomech. Eng. 130(4), 044504 (2008)
9. Elson, E.L., Fried, E., Dolbow, J.E., Genin, G.M.: Phase separation in biological membranes:
integration of theory and experiment. Annu. Rev. Biophys. 39, 207-226 (2010)
10. Massouros, P.G., Genin, G.M.: The steady-state response of a Maxwell viscoelastic cylinder
to sinusoidal oscillation of its boundary. Proc. Roy. Soc. Lond. A 464(2089), 207-221 (2008)
11. Nekouzadeh, A., Pryse, K.M., Elson, E.L., Genin, G.M.: Stretch-activated force shedding,
force recovery, and cytoskeletal remodeling in contractile fibroblasts. J. Biomech. 41(14),
2964-2971 (2008)
12. Nekouzadeh, A., Rudy, Y.: Continuum molecular simulation of large conformational changes
during ion-channel gating. PLoS One 6(5), e20186 (2011)
13. Qiu, H., Zhu, Y., Sun, Z., Trzeciakowski, J.P., Gansner, M., Depre, C., Resuello, R.R.,
Natividad, F.F., Hunter, W.C., Genin, G.M., Elson, E.L., Vatner, D.E., Meininger, G.A.,
Vatner, S.F.: Vascular smooth muscle cell stiffness as a mechanism for increased aortic
stiffness with aging. Circ. Res. 107(5), 615-619 (2010)
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