Biomedical Engineering Reference
In-Depth Information
FIGURE 7.9
Characterization of IO nanoparticles. (A) TEM image of the hydrophobic inorganic
core of the IO NPs, showing a diameter around 27 ± 5 nm (relative standard deviation of 9.5% for
n
= 50); (B) TEM image of antibody conjugated biocompatible water-soluble IO, IO-Ab, using
phosphotungstic acid for background staining; (C) light scattering properties of biocompatible
water-soluble IO showing a hydrodynamic size around 33 nm with a zeta potential of −51 mV, and
IO-Ab showing a hydrodynamic size around 41 nm and a zeta potential of −36 mV; (D) agarose gel
electrophoresis of biocompatible water soluble IO (on left) and IO-Ab (on right), the electric pole
is negative for top and positive for the bottom.
Courtesy of Xu, et al.
285
(For color version of this
figure, the reader is referred to the online version of this topic)
