Biomedical Engineering Reference
In-Depth Information
Fig. 2.14
The hybrid integrated circuit/microfluidic chip fuses two vesicles
Fig. 2.15 Cell fusion was performed on the integrated circuit/microfluidic chip. Dielectrophoresis
was used to arrange the cells in different configurations ( a , b ), and electrofusion and chemical
fusion were used to merge neighboring cells
Cells were fused both stochastically and deterministically-stochastic pairing results
in random cells being fused together, while deterministic pairing ensures that each
pair contains one cell from both cell lines. Viable fused cells with a mean yield
of 89 % were observed. Figure 2.15 a shows multiple pairs of cells being aligned in
rows and fused, and Fig. 2.15 b shows cells being arranged in a circle for fusion.
Search WWH ::

Custom Search