Biomedical Engineering Reference
In-Depth Information
Fig. 2.8
A video is played on the chip where thousands of yeast cells are moved in the shape of a
dancer. The video is sent to the chip as a GIF file
2.4.2
Deform
The chip can be used to deform vesicles into different shapes, shown in Fig.
2.9
[
10
]. This has important implications for single-vesicle and single-cell rheology
where microscopic control is essential for studying these complex systems. It
represents an alternative to microcontact patterning [
20
] and other existing methods
for single-cell studies. Figure
2.9
shows vesicles being stretched, compressed, and
being deformed into various shapes with flat edges. The first column in the figure
shows the active pixels shaded. The second column shows the results of electric
field simulations mapping the field amplitude where brighter red colors represent
stronger fields. The third column shows images of vesicles being deformed. The
vesicles are approximately 50m in diameter and can be stretched, compressed,
and deformed into squares, diamond, and hexagons.
