Biomedical Engineering Reference
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Fig. 9.10 Cellular detection
via DMR .( a ) The detection
limit by DMR is nearly at
single cell level (
2 cells),
which is superior to the
current clinical methods
(cytology and histology). ( b )
The uptake of unmodified
MNPs by cells was exploited
to estimate the cell population
in the samples. The measured
R 2 was linearly
proportional to the cell
concentrations. Importantly,
the linear trends were
statistically identical in
different cell types. ( c )The
analytical accuracy of the
NMR was benchmarked
against flow cytometry and
Western blotting by
measuring HER2/ neu
expression on breast cancer
cells (Adopted from [ 28 ].
Copyright 2009 National
Academy of Sciences, USA)
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