Biomedical Engineering Reference
In-Depth Information
Fig. 9.10
Cellular detection
via DMR
.(
a
) The detection
limit by DMR is nearly at
single cell level (
2 cells),
which is superior to the
current clinical methods
(cytology and histology). (
b
)
The uptake of unmodified
MNPs by cells was exploited
to estimate the cell population
in the samples. The measured
R
2
was linearly
proportional to the cell
concentrations. Importantly,
the linear trends were
statistically identical in
different cell types. (
c
)The
analytical accuracy of the
NMR was benchmarked
against flow cytometry and
Western blotting by
measuring HER2/
neu
expression on breast cancer
cells (Adopted from [
28
].
Copyright 2009 National
Academy of Sciences, USA)
