Biomedical Engineering Reference
In-Depth Information
Fig. 5.19
(
a
) A schematic diagram of a DMFET and the experimental setup for the charge-
pumping measurements [
52
]. (
b
) Experimental results comparing the measured I
cp
values
before and after the binding of biotin-streptavidin in the nanogap. When the concentration of a
biotin/phosphate-buffered saline (PBS) solution is fixed at 10 mM, the modulation of I
cp
depends
on the streptavidin/PBS solution concentration, which ranged from 20 pM to 2 nM in this case [
51
]
(Copyright 2010 American Institute of Physics)
Fig. 5.20
Measured I
cp
values as a function of the frequency. The sensing margin is increased
in the low-frequency range. The sensitivity can fall below the picomolar concentration range [
52
]
(Copyright 2010 American Institute of Physics)