Biology Reference
In-Depth Information
FIGURE 7.2
Analysis of 5-HT
4
receptor dimers by Western blot. All receptors used, N-terminally tagged
with c-Myc epitope, have been transiently expressed in COS-7 cells and processed as
described in the main text. Transfected variant or mutant receptors are indicated above
the blots. (A) Transfection of each variant separately show the formation of dimers and
monomers of (a), (b), (e), or (f) variants. (B) When variants (a) and (e) are cotransfected (right
line), a band of an intermediate size between (a) and (e) homodimer bands appears that
corresponds to the formation of a dimer between (a) and (e) protomers (indicated with an
