MICRO-AND NANOTECHNOLOGIES TO ENGINEER BONE REGENERATION - Micro and Nanotechnologies in Engineering Stem Cells and Tissues - page 224

FIGURE 10.2 Scanning electron microscope micrographs of cells cultured on (a) PLGA
scaffolds, (b) PLGA-HAp, and (c) Ap-coated PLGA-HAp scaffolds for 28 days. Large
numbers of nodules such as minerals (indicated as arrows) were observed on the surface
of Ap-coated PLGA-HAp scaffolds. Adapted from Ref. [9] # ACS 2010.

toughness of the composites by 28 and 50%, respectively. Further increase in
MWCNT loading concentration decreased the strength and toughness of the
composites due to formation of MWCNT aggregates resulting in weakness at the
interface between nHAp and MWCNTs (Fig. 10.3). 38
nHAp-polymeric scaffolds seeded with marrow-derived g/10

mesenchymal stromal cells (MSCs) have been reported to stimulate the growth
of MSCs at concentrations less than 20

(40 and 200 m

g/10 4 m cells. However, at higher