Biomedical Engineering Reference
In-Depth Information
10
Setting up an 'omics platform
in a small biotech
Jolyon Holdstock
Abstract:
Our current 'omics platform is the product of several years
of evolution responding to new technologies as they have emerged
and also increased internal demand for tools that the platform
provides. The approaches taken to select software are outlined as
well as any problems encountered and the solutions that have
worked for us. In conjunction lessons learnt along the way are
detailed. Although sometimes ignored, the range of skills required
to use and maintain the platform are described.
Key words:
microarrays; disaster recovery; bioinformatic tools;
skill sets.
10.1 Introduction
Founded in 1995 by the pioneer of Southern blotting and microarray
technologies, Professor Sir Edwin Southern, Oxford Gene Technology
(OGT) is focused on providing innovative clinical genetics and diagnostic
solutions to advance molecular medicine. OGT is based in Yarnton,
Oxfordshire and is a rapidly growing company with state-of-the-art
facilities and over 60 employees. The key focus areas of OGT are:
■
tailored microarray [1] and sequencing services enabling high-quality,
high-throughput genomic studies;
■
cytogenetics products and services delivering the complete
oligonucleotide array solution for cytogenetics;
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