Biomedical Engineering Reference
In-Depth Information
Map 2.0 data set (E-MTAB-513). These experiments call for different
statistics and visualization approaches entirely, and the Atlas team have
started work on making this possible.
9.4 Deploying Atlas in the enterprise
9.4.1 Rationale and requirements for an
'in-house' Atlas
The EBI public Gene Expression Atlas web site has proven to be a
valuable resource for mining public expression data. Having an 'in-house'
installation of the system provides the added advantage of combining
internal, proprietary data with the public content in one easy to use
system. Furthermore, an internal system can be customized and extended
and may also be integrated with other internal systems.
An open source system will typically have a shorter release cycle than
most commercial systems and is likely to require some additional testing.
Therefore, it is highly desirable to have a research computing environment
where databases, data fi les and applications can be deployed without a
formal change control processes. Pfi zer Research Business Technology
supports global and local computational biology groups with an
application hosting environment that uses a hybrid support model where
system management and confi guration are under the control of the data
center platform and operations teams using standard processes.
Applications are deployed using non-privileged service accounts used by
a deployment team. Databases are managed in a similar fashion, using an
Oracle instance backed-up and managed by the corporate database
operations team. A local representative in the application support group
has system privileges enabling them to create, extend, and tune the Atlas
database. These environments are used to support both test and quasi-
production environments, enabling new releases to be evaluated offl ine
and quickly released for general use after testing and evaluation.
9.4.2 Deployment and customization of the
Pfi zer Gene Expression Atlas
Deployment of the standalone Atlas follows procedures provided by the
EBI Atlas team. The database fi le is downloaded and deployed on a
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