Biomedical Engineering Reference
In-Depth Information
7
Investigation-Study-Assay, a toolkit
for standardizing data capture
and sharing
Philippe Rocca-Serra,
Eamonn Maguire, Chris Taylor,
Dawn Field, Timo Wittenberger,
Annapaola Santarsiero, Alejandra Gonzalez-
Beltran and Susanna-Assunta Sansone
Abstract:
This chapter introduces the problems experimentalists in
all sectors face in utilizing third party data sets given the unhelpful
wealth of formats and terminologies and the consequent mountain
of technical frameworks needed to achieve data interoperability. We
argue on the importance of a complementary set of open standards,
the challenges we must overcome and the role the BioSharing effort
is set to play. As an example of progress, we present the open source
ISA software solution in action during the curation of the InnoMed
PredTox data set, along with its growing active developer and user
community, including academia and industrial sectors, such as The
Novartis Institutes for BioMedical Research and Janssen Research
& Development.
Key words:
data management; biocuration; community standards;
ontology; open source software; InnoMed PredTox; BioSharing,
ISA.
The successful integration of heterogeneous data from multiple
providers and scientifi c domains is already a major challenge within
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