Biology Reference
In-Depth Information
Svelander L, Erlandsson-Harris H, Astner L, Grabowska U, Klareskog L, Lindstrom E, Hewitt E
(2009) Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation
evoked by collagen-induced arthritis in mice. Eur J Pharmacol 613:155-162
Szpaderska AM, Frankfater A (2001) An intracellular form of cathepsin B contributes to invasive-
ness in cancer. Cancer Res 61:3493-3500
Tai IT, Tang MJ (2008) SPARC in cancer biology: its role in cancer progression and potential for
therapy. Drug Resist Updat 11:231-246
Takahashi H, Ishidoh K, Muno D, Ohwada A, Nukiwa T, Kominami E, Kira S (1993) Cathepsin L
activity is increased in alveolar macrophages and bronchoalveolar lavage fluid of smokers. Am
Rev Respir Dis 147:1562-1568
Taleb S, Cancello R, Cl´ment K, Lacasa D (2006) Cathepsin S promotes human preadipocyte
differentiation: possible involvement of fibronectin degradation. Endocrinology 147:4950-4959
Tezuka K, Tezuka Y, Maejima A, Sato T, Nemoto K, Kamioka H, Hakeda Y, Kumegawa M
(1994) Molecular cloning of a possible cysteine proteinase predominantly expressed in osteo-
clasts. J Biol Chem 269:1106-1109
Tolosa E, Li W, Yasuda Y, Wienhold W, Denzin LK, Lautwein A, Driessen C, Schnorrer P, Weber
E, Stevanovic S, Kurek R, Melms A, Bromme D (2003) Cathepsin V is involved in the
degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J
Clin Invest 112:517-526
Tortorella MD, Pratta M, Liu RQ, Austin J, Ross OH, Abbaszade I, Burn T, Arner E (2000) Sites of
aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4). J Biol Chem
275:18566-18573
Turk B (2006) Targeting proteases: successes, failures and future prospects. Nat Rev Drug Discov
5:785-799
Turk V, Turk B, Turk D (2001) Lysosomal cysteine proteases: facts and opportunities. EMBO J
20:4629-4633
Umezawa H (1982) Low-molecular-weight enzyme inhibitors of microbial origin. Annu Rev
Microbiol 36:75-99
Vasiljeva O, Dolinar M, Pungercar JR, Turk V, Turk B (2005) Recombinant human procathepsin S
is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans.
FEBS Lett 579:1285-1290
Vasiljeva O, Reinheckel T, Peters C, Turk D, Turk V, Turk B (2007) Emerging roles of cysteine
cathepsins in disease and their potential as drug targets. Curr Pharm Des 13:387-403
Velasco G, Ferrando AA, Puente XS, Sanchez LM, Lopez-Otin C (1994) Human cathepsin O.
Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia
coli, and expression analysis in human tissues. J Biol Chem 269:27136-27142
Vinardell T, Dejica V, Poole AR, Mort JS, Richard H, Laverty S (2008) Evidence to suggest that
cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis. Osteoar-
thritis Cartilage 17:375-383
Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP (2006) Cathepsin
S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem
281:6020-6029
Watari M, Watari H, Nachamkin I, Strauss JF (2000) Lipopolysaccharide induces expression of
genes encoding pro-inflammatory cytokines and the elastin-degrading enzyme, cathepsin S, in
human cervical smooth-muscle cells. J Soc Gynecol Investig 7:190-198
Westling J, Fosang AJ, Last K, Thompson VP, Tomkinson KN, Hebert T, McDonagh T, Collins-
Racie LA, LaVallie ER, Morris EA, Sandy JD (2002) ADAMTS4 cleaves at the aggrecanase
site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in
the aggrecan interglobular domain. J Biol Chem 277:16059-16066
Wex T, Buhling F, Wex H, Gunther D, Malfertheiner P, Weber E, Bromme D (2001) Human
cathepsin W, a cysteine protease predominantly expressed in NK cells, is mainly localized in
the endoplasmic reticulum. J Immunol 167:2172-2178
