Biology Reference
In-Depth Information
Liang X, Arunima A, Zhao Y, Bhaskaran R, Shende A, Byrne Ts, Fleeks J, Palmier Mo,
Doren Van Sr (2010) Apparent tradeoff of higher activity in mmp-12 for enhanced stability
and flexibility in mmp-3. Biophys J 99:273-283
Maskos K (2005) Crystal structures of mmps in complex with physiological and pharmacological
inhibitors. Biochimie 87:249-263
Minond D, Lauer-Fields Jl, Cudic M, Overall Cm, Pei D, Brew K, Visse R, Nagase H, Fields Gb
(2006) The roles of substrate thermal stability and p2 and p1
0
subsite identity on matrix
metalloproteinase triple-helical peptidase activity and collagen specificity. J Biol Chem
281:38302-38313
Monaco S, Gioia M, Rodriguez J, Fasciglione Gf, Di Pierro D, Lupidi G, Krippahl L, Krippahl L,
Marini S, Coletta M (2007) Modulation of the proteolytic activity of matrix metalloproteinase-2
(gelatinase a) on fibrinogen. Biochem J 402:503-513
Morgunova E, Tuuttila A, Bergmann U, Isupov M, Lindqvist Y, Schneider G, Tryggvason K
(1999) Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed.
Science 284:1667-1670
Murphy G, Allan Ja, Willenbrock F, Cockett Mi, O'connell Jp, Docherty Aj (1992) The role of the
c-terminal domain in collagenase and stromelysin specificity. J Biol Chem 267:9612-9618
O'farrell Tj, Pourmotabbed T (1998) The fibronectin-like domain is required for the type v and xi
collagenolytic activity of gelatinase b. Arch Biochem Biophys 354:24-30
Orgel Jp, Irving Tc, Miller A, Wess Tj (2006) Microfibrillar structure of type i collagen in situ.
Proc Natl Acad Sci USA 103:9001-9005
Overall Cm (2001) Matrix metalloproteinase substrate binding domains, modules and exosites.
Overview and experimental strategies. Methods Mol Biol 151:79-120
Overall Cm (2002) Molecular determinants of metalloproteinase substrate specificity: Matrix
metalloproteinase substrate binding domains, modules, and exosites. Mol Biotechnol 22:51-86
Overall Cm, Butler Gs (2007) Protease yoga: extreme flexibility of a matrix metalloproteinase.
Structure 15:1159-1161
Palmier Mo, Fulcher Yg, Bhaskaran R, Duong Vq, Fields Gb, Van Doren Sr (2010) Nmr and
bioinformatics discovery of exosites that tune metalloelastase specificity for solubilized elastin
and collagen triple helices. J Biol Chem 285(40):30918-30930
Patterson Ml, Atkinson Sj, Knauper V, Murphy G (2001) Specific collagenolysis by gelatinase a,
mmp-2, is determined by the hemopexin domain and not the fibronectin-like domain. FEBS
Lett 503:158-162
Pelman Gr, Morrison Cj, Overall Cm (2005) Pivotal molecular determinants of peptidic and
collagen triple helicase activities reside in the s3
0
subsite of matrix metalloproteinase
8 (mmp-8): The role of hydrogen bonding potential of asn188 and tyr189 and the connecting
cis bond. J Biol Chem 280:2370-2377
Perumal S, Antipova O, Orgel Jp (2008) Collagen fibril architecture, domain organization, and
triple-helical conformation govern its proteolysis. Proc Natl Acad Sci USA 105:2824-2829
Ra Hj, Harju-Baker S, Zhang F, Linhardt Rj, Wilson Cl, Parks Wc (2009) Control of promatrilysin
(mmp7) activation and substrate-specific activity by sulfated glycosaminoglycans. J Biol
Chem 284:27924-27932
Richardson Jl, Kroger B, Hoeffken W, Sadler Je, Pereira P, Huber R, Bode W, Fuentes-Prior P
(2000) Crystal structure of the human alpha-thrombin-haemadin complex: an exosite
ii-binding inhibitor. EMBO J 19:5650-5660
Rosenblum G, Van Den Steen Pe, Cohen Sr, Grossmann Jg, Frenkel J, Sertchook R, Slack N,
Strange Rw, Opdenakker G, Sagi I (2007) Insights into the structure and domain flexibility of
full-length pro-matrix metalloproteinase-9/gelatinase b. Structure 15:1227-1236
Saffarian S, Collier Ie, Marmer Bl, Elson El, Goldberg G (2004) Interstitial collagenase is a
Brownian ratchet driven by proteolysis of collagen. Science 306:108-111
Schilling O, Overall Cm (2008) Proteome-derived, database-searchable peptide libraries for
identifying protease cleavage sites. Nat Biotechnol 26:685-694