Biomedical Engineering Reference
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65
65
60
60
55
55
50
0% GS
50
0 % Alm
1.36 % GS
0.5 % Alm
45
45
0.0
0.2
0.4
0.6
0.8
1.0
0.0
0.5
1.0
1.5
2.0
2.5
3.0
Alm mole % in DEPE
GS mole % in DEPE
65
65
0% (LA)
60
60
0.2 % (LA)
12
0 % Alm
55
55
0.5 % Alm
50
50
45
45
0.0
0.2
0.4
0.6
0.8
1.0
0.0
0.5
1.0
Alm mole % in DEPE
(LA)
12
mole % in DEPE
Fig. 3.10
Effect of the binary presence of AMPs on
T
H
in DEPE dispersions [
1
]
that induced by 0.6mole% Alm alone, and continues experiencing quick drops with
increasing (LA)
12
, before experiencing saturation.
In a reverse investigation, at low Alm (Alm-GS ratio between 0 and 0.184) with
1.36% GS,
T
H
decreases considerably, experiencing higher drops than without GS,
but requiring a relatively higher Alm level (Alm-lipid ratio of 0.25%). With increas-
ing Alm (Alm-GS ratio between 0.184 and 0.22)
T
H
increases substantially, over-
shooting the Alm-alone value, and again slightly decreasing with a further increased
Alm level (Alm-GS ratio between 0.22 and 0.44). However, at a still higher Alm level
(Alm-GS ratio over 0.44),
T
H
decreases sharply and drops to values which are con-
siderably lower than the Alm-alone values, and continues to modestly decrease with
increasing Alm/GS ratios. Due to the effects of low Alm [Alm-(LA)
12
ratio between
0 and 1.5] with 0.2mole% (LA)
12
, we observe
T
H
to modestly decrease, but then
[Alm-(LA)
12
ratio over 1.5]
T
H
continues to experience quick and continuous drops.
Interestingly, non-transmembrane GS enhances, but transmembrane (LA)
12
reduces
the ultra-low level Alm-induced drop in
T
H
, which is identical to a transmembrane
property-dependent trend observed in their independent (low level) effects [(LA)
12
,
Alm and GS cause negligible, moderate and substantial drops in
T
H
], although at a
cost of a little higher Alm in the former but a little lower Alm in the latter cases. Sim-
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