Membrane-Related Diseases - Membrane Biophysics, Biological and Medical Physics, Biomedical Engineering - page 165

Table 7.2 Initial
concentrations of the main
ionic species

Ion Initial concentration (mM)

Na + apical 130

K + apical 4

Cl − apical 134

HCO 3 apical

24

Na + basolateral 130

K + basolateral 4

Cl − basolateral 134

HCO 3 basolateral 24

Na + intracellular 20

K + intracellular 110

Cl − intracellular

45

HCO 3 intracellular 24

Models that quantify the functioning of the membrane and its components in
health and disease are ultimately the area where biophysics can demonstrate its great
value in medical research advances.

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