Biomedical Engineering Reference
In-Depth Information
Fig. 7.8
Model of ion trans-
port in the pancreatic ductal
epithelium cells
Cell
luminal
basolateral
H
2
O + CO
2
CO
2
HB
H
2
CO
3
B
-
+ H
+
+ HCO
3
-
HCO
3
-
Cl
-
Cl
-
H
+
nHCO
3
-
HCO
3
-
Na
+
H
+
Na
+
Cl
-
Na
+
3Na
+
2K
+
K
+
Na
+
K
+
H
2
O
G
Na
−
HCO
3
[
Na
+
]
bl
[
HCO
3
]
2
RT
−
[
Na
+
]
c
[
HCO
3
]
bl
PD
bl
2
RT
c
PD
bl
×
e
−
(
1
−
n
)
×
F
×
×
e
(
1
−
n
)
×
F
×
K
c
Na
K
c
HCO
3
K
c
Na
K
c
HCO
3
J
Na
−
HCO
3
=
A
+
B
(7.10)
where
e
(
1
−
n
)
×
F
×
HCO
3
]
Na
+
]
bl
[
n
bl
R
l
/
k
×
[
PD
bl
2
RT
=
+
A
K
c
Na
K
c
HCO
3
1
HCO
3
]
Na
+
]
c
Na
+
]
c
[
c
+
[
K
c
Na
+
[
×
K
c
Ka
K
c
HCO
3
and
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