Biomedical Engineering Reference
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0.30
0.31
0.32
0.33
10
150000
10
150000
10
100000
10
100000
10
50000
10
50000
10
0
10
0
0.30
0.31
0.32
0.33
r
0.27
0.28
0.29
0.30
10
150000
10
150000
10
100000
10
100000
10
50000
10
50000
10
0
10
0
0.27
0.28
0.29
0.30
r
Fig. 5.18
A plot of the energy as a function of the reaction coordinate (r) for an Alm channel in lipid
bilayer energetics at different values of
r
LL
(left
→
right:
r
LL
=
6
.
48074, 6
.
9282 (
lower panel
),
7
74597 Å (
upper panel
)) for the first- (single-dashed curve) and second-(double-dashed
curve) order lipid screening.
q
L
.
34847, 7
.
/
q
Alm
=
0
.
0025
the calculation of
G
I
,
II
increases (shifts toward higher values) in linear propor-
tionality to
r
LL
for both the first- and second-order lipid screening.
The most dramatic theoretical result is illustrated in Fig.
5.23
, where
G
I
,
II
increases exponentially with the increase of
d
0
−
l
(here we have rephrased the order
of screening by
d
0
−
l
):
G
I
,
II
∝
exp
(
d
0
−
l
).
(5.30)
G
def
, the dissociation force:
Consequently, as
G
I
,
II
is proportional to
∂
G
I
,
II
(
d
0
−
l
)
F
dis
=−
−
(5.31)
∂(
d
0
−
l
)
also follows an exponential relation:
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