Immunology Basics - Immunological Computation: Theory and Applications - page 23

15. Compare the roles of B- and T cells in immune response.
16. What are the two selection processes that are used in T cell maturation?
17. What is tra cking (or homing)?
18. What is a GC? What is the role of a GC in the immune system?
19. Under what conditions does a GC start forming in a lymph node?
20. What happens when the number of centrocycles increases in the GC? Defi ne.
21. Which are the two stages involved in the centrocycle? Explain briefl y.
22. W hat happens when a high rate of mutation couples with clonal competition?
Discuss its eff ects.
23. Match immune concepts in column A with their corresponding concepts in
column B.

Immune System Structure

Column A Column B

Bone marrow Direct the cellular-mediated immune response and

phagocytosis

Hematopoiesis Its function is to produce mature T cells

Thymus Formation of blood cells process

Spleen Specialized cells, which engulf large particles by a

process called phagocytosis

Lymph nodes Organs where all the immune system's cells are initially

derived from

Cytokines It consists of an outer cortex and an inner medulla

Helper T cells Antigen-binding proteins present on a B cell membrane

Antibodies Aid B cells to perform antigen recognition by releasing

cytokines

MHC proteins It is an immunologic fi lter of the blood

Macrophages They act as “sign posts” that display peptides on the

surface of a host cell

Complement system System of molecules that leads a sequence of events

on the surface of a pathogen that helps destroy it

24. Complete the missing words (fi ll in the blanks) in the following diagram.

Biological defense system

defense mechanism defense mechanism

Third line defense:

First line defense: Second line defense:

immunity

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∗

∗

∗
∗
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Skin
Skin's secretion
Mucous membranes

Antimicrobial proteins

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