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In-Depth Information
Antigen receptor
Antigens
Variety of B cells
Cell proliferation
Clone of plasma cells
Clone of memory cells
Antibodies secreted
into circulation
Figure 1.10
Basic concepts of the clonal expansion.
1.3.4.1 Germinal Center
Lymph nodes are small nodular aggregates of lymphocyte-rich tissue situated along
lymphatic channels throughout the body. A lymph node consists of an outer cortex
and an inner medulla; and lymph nodes contain aggregates of cells called follicles,
and evolve a specialized area called
germinal center
(GC).
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