Information Technology Reference
In-Depth Information
Secondary immune
response to antigen A
Second exposure
to antigen A,
first exposure
to antigen B
10
4
First exposure
to antigen A
10
3
10
2
Primary immune
response to antigen A
Primary immune
response to antigen B
10
1
Antibodies to A
Antibodies to B
10
0
0
7
14
21
28
35
42
49
56
Time (days)
Figure 1.8
Immunological memory—primary and secondary immune
responses.
Antigen-presenting cell
(an infected cell)
Antigen-presenting cell
(a macrophage)
Class l MHC molecule
Class ll MHC molecule
Antigen fragment
Antigen fragment
T cell receptor
T cell receptor
Cytotoxic T cell (T
C
)
Helper T cell (T
H
)
(a)
(b)
Figure 1.9 T cell recognition. T cells can only recognize antigen associated
with MHC molecules on cell surfaces. (a) T cell recognition of class I MHC
molecules, (b) T cell recognition of class II MHC molecules. (From Coutinho,
A.,
Ann. of Immunol. (Inst. Pasteur.)
, 131D, 1980; Paul, W. E.,
Fundamental
Immunology
. Raven Press, New York, 1993.)
Search WWH ::
Custom Search