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Input data
Antigen
Signal matrix
Data sampling phase
Immune dendritic
Maturation phase
More danger signals
More safe signals
Semimature
Mature
Analysis
Figure 7.6
Schematic overview of the DCA.
3. Compute complement set to 1 and 2.
4. Create immature DCs (iDCs) with signal receptors randomly drawn from
the complement signal set and with antigen receptors randomly drawn from
the complement system call set.
5. Create naive T cells (nTCs) with antigen receptors randomly drawn from
complement system call set.
6. iDCs are continually exposed to sample signals and antigens, respectively.
7. If during its lifetime an iDC's signal receptor matches a signal, it becomes a
mature DC (mDC) and migrates.
8. If an iDC has not migrated at the end of its lifetime, it becomes a semimature
DC (smDC) at the end of its lifetime and migrates.
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