Biomedical Engineering Reference
In-Depth Information
1.5.2
Plasmapheresis
Plasmapheresis separates plasma and blood cells. The filtration flux per unit of
plasma filter area is approximately proportional to the wall shear rate at least up
to 7500/s and depends on the effective membrane length
L
−
1
/
3
[
27
]. Pulsatile
flow with the time-mean flow rate equal to the steady flow enhances the filtration
flux, with optimal modulation frequency 1 Hz and volume amplitude 1.5 ml [
28
].
Mathematical and numerical analysis of filtration across a fibrous medium has been
performed [
29
], using a homogeneization technique [
30
-
36
].
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