Biomedical Engineering Reference
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Hypertension induces wall remodeling. The endothelial cells display structural
changes associated with increased media thickness due to hypertrophy of smooth
myocytes [
703
]. The amount of elastin does not change significantly, whereas the
collagen concentration strongly increases. Concentration of TGF
produced by
aortas of hypertensive rats rises up to 3-fold with respect to those of normotensive
rats [
704
].
β
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