Environmental Engineering Reference
In-Depth Information
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EPA-R824726
Fermentation of Sugars to 1,2-Propanediol by Clostridium
thermosaccharolyticum (PI: Cameron, University of Wisconsin-Madison)
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EPA-R826116
Environmentally Benign Synthesis of Resorcinol from Glucose (PI:
Frost, Michigan State University)
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NSF-9819957; EPA-R826729
Metabolic Engineering of Methylotrophic Bacteria for
Conversion of Methanol to Higher Value-Added Products (PI: Lidstrom, University
of Washington)
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NSF-9985421
Metabolic Engineering of Carbon Fixation and Utilization for
Biopolymer Production by Cyanobacteria (PI: Stephanopoulos, MIT)
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NSF-0118961
Metabolic Engineering of Bacillus for Enhanced Product Yield (PI:
Ataai, University of Pittsburgh)
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NSF-0124401
Metabolic Engineering of Monooxygenases for 1-Naphthol and
Styrene Epoxide Formation (PI: Wood, University of Connecticut)
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EPA-R829589
Analysis and Management of Fluxes in Bacillus Pathways for
Pesticide and Protein Production (PI: Grossmann, Carnegie-Mellon University)
The engineering of microorganisms and enzymes to withstand side reactions or industrial
bioreactor conditions, often facilitating more rapid and/or less expensive production, is
another prominent goal of metabolic and genetic engineering that has been addressed.
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NSF-9817621
Improving Resistance to Enzyme Alkylation During Enzyme-
Catalyzed Production of Acrylamide (PI: Oriel, Michigan State University)
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NSF-9911231
; EPA-R828562 Metabolic Engineering of Solvent Tolerance in
Anaerobic Bacteria (PI: Papoutsakis, Northwestern University)
3. TSE Contributions to Bioreactor Technology, Bioseparations, and
Bioprocessing
A fundamental component of any bioreactor-based sustainable technology is the ability to
use non-toxic, biodegradable and/or environmentally benign solvents for the separation and
processing of the desired bioproducts. The TSE Program has contributed substantially to this
effort, funding projects to develop supercritical CO2, supercritical and near-supercritical
water, polyglycols, and ionic liquids as solvents, as well as processes that avoid the need for
solvents altogether.
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NSF-96 13258
Coexisting Chemical-Biological Modifications of Chlorinated
Solvents as a Basis for Waste Reduction in Pollution Prevention (PI: Watts,
Washington State University)
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NSF-9817069
Novel Compressed Solvent Extraction Processes for Enhanced
Biomass Conversion by Thermophilic Bacteria (PI: Knutson, University of
Kentucky)
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EPA-R826113
Synthetic Methodology “Without Reagents” Tandem Enzymatic and
Electrochemical Methods for the Manufacturing of Fine Chemicals (PI: Hudlicky,
University of Florida)
